Locally advanced prostate cancer effected by the tumor immunoenvironment
نویسندگان
چکیده
منابع مشابه
Locally advanced prostate cancer
The management of all stages of prostate cancer is an increasingly complex process and involves a variety of available treatments and many disciplines. Despite prostate-specific antigen (PSA) testing, the presentation of prostate cancer at a locally advanced stage is common in the UK, accounting for one-third of all new cases. There is no universally accepted definition of locally advanced pros...
متن کاملTreatment strategies for locally advanced prostate cancer.
With the increasing aged population, prostate cancer has become one of the commonest malignant tumors in the United States. The incidence of prostate cancer is the highest among malignant tumors in males, and the mortality rate is the second highest following lung cancer. Even when prostate cancer is diagnosed to be in the early stage preoperatively, its excised lesions are often judged pathohi...
متن کاملManagement of locally advanced prostate cancer
The management of prostate cancer involves the consideration of a number of clinical, biological and patient factors in order to determine the most appropriate treatment. These include the clinical stage of the tumour, the presence or absence of high-risk features, and individual patient factors such as comorbidities and performance status. There is then careful discussion between the patient a...
متن کاملPhase I study with an autologous tumor cell vaccine for locally advanced or metastatic prostate cancer.
PURPOSE To attempt the isolation and primary culture of prostate tumor cells, to use the cultured cells for active immunotherapy, and to evaluate the safety and efficacy in a Phase I clinical trial. MATERIALS AND METHODS Tumor fragments were collected from 50 patients with prostate-specific antigen (PSA) > or = 10 ng/mL, < or = cT2 PCa who underwent radical retropubic prostatectomy (RRP) and ...
متن کاملRole of Surgery in locally advanced prostate cancer
UNLABELLED A significant proportion of patients present with locally advanced prostate cancer with inherent higher risk of local recurrence and systemic relapse after initial treatment. Recent literature favors combination of radiation therapy and extended hormonal therapy for this subset of patients. The effectiveness of Radical prostatectomy (RP) alone for locally advanced prostate cancer is ...
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ژورنال
عنوان ژورنال: European Urology Open Science
سال: 2020
ISSN: 2666-1683
DOI: 10.1016/s2666-1683(20)32988-8